**This AI Predicts Your Disease Risks 10 Years in Advance**
*By Mudit Dube | Sep 18, 2025 05:04 pm*
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### What’s the Story?
A team of scientists has developed a groundbreaking artificial intelligence (AI) tool capable of predicting an individual’s risk for over 1,000 diseases. The innovative system, dubbed **Delphi-2M**, can also forecast changes in health conditions up to a decade in advance.
Published in the journal *Nature*, this research highlights the incredible potential of generative AI to model human disease progression on a large scale, paving the way for advancements in personalized healthcare.
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### How Delphi-2M Works
Delphi-2M operates using algorithmic concepts similar to those behind large language models (LLMs). It predicts the likelihood of developing a wide range of diseases, including cancer, diabetes, heart disease, and respiratory disorders.
The tool analyzes a combination of “medical events” from a patient’s history—such as diagnosis dates—and lifestyle factors, including obesity status, smoking or drinking habits, age, and sex.
Delphi-2M was trained on anonymized data sourced from two extensive healthcare databases: the UK Biobank study, which includes 400,000 participants, and Denmark’s national patient registry, covering 1.9 million patients.
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### Potential Impact on Personalized Healthcare
Unlike traditional medical risk assessments, Delphi-2M forecasts health risks as rates over time, similarly to how weather forecasts predict changes. Ewan Birney, interim executive director of EMBL, stated that patients could benefit from this AI tool within the next few years.
He envisions a future where clinicians utilize systems like Delphi-2M to identify major health risks early, empowering patients through lifestyle modifications to reduce those risks. This represents a significant leap forward in personalized healthcare and proactive disease prevention.
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### Advantages Over Existing Methods
Current risk assessment tools, such as Qrisk, typically focus on single diseases and offer limited long-term predictions. Ewan Birney emphasized that Delphi-2M’s key strength lies in its ability to evaluate multiple diseases simultaneously over extended periods.
The research team confirmed that Delphi-2M predicts disease rates based on an individual’s past health history with accuracy comparable to existing single-disease models, but with broader and more dynamic capabilities.
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### Future Prospects: Revolutionizing Healthcare
Professor Moritz Gerstung from the German Cancer Research Center described Delphi-2M as a major step toward a deeper understanding of human health and disease progression.
He believes generative AI models like this will soon play a crucial role in personalizing care and anticipating healthcare needs on a large scale.
Delphi-2M exemplifies how AI can revolutionize healthcare by providing early predictions of individual health risks, thus enabling more effective and timely preventative measures.
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*Stay tuned as AI continues to transform the future of medicine and patient care.*
https://www.newsbytesapp.com/news/science/delphi-2m-ai-tool-predicts-risk-of-over-1-000-diseases/story